Osteoporosis

Reduction in bone mass via loss of matrix
Excessive bone loss
Normal mineral:matrix ratio

Causes
Old age (post-menopause)
Endocrine
 - premature ovarian failure (early menopause)
- Cushings
- thyrotoxicosis
Drugs
Steroids
Heparin

Ix
pl Bone profile = normal
DEXA
- Identify fast bone losers
- Monitor therapy (HRT, bisphosphonates)