Bone Marrow Failure

Marrow Failure
=
Pancytopenia i.e.
Anaemia
Leucopenia

Thrombocytopenia

2 types

- Hypocellular (empty)

- Infiltrated (competes with normal marrow & normal haemopoetic cells)

Hypocellular
Aplastic Anaemia
Myelodysplasia (can be cellular)
CTx
RTx

Infiltrated
2ry causes (lung/prostate/breast/thyroid/kidney)
Acute leukaemias
Lymphomas
Myeloma