Diverticular Disease

Diverticulosis
Outpouchings of mucosa through bowel wall
Diverticulitis
Inflamed diverticula
Diverticular Disease
Symptomatic diverticulosis
Solitary & multiple diverticula poss throughout colon/smI
*sigmoid colon

Epidemiology
Affects Western, elderly population
>60% >80
Rare in Asia & Africa

Pathology
60% only in sigmoid
Never rectum
SmI diverticula
*duodenum
Incidental
Rarely Sy

NB
Diverticulosis - if Right-sided colon = ?different disease (*younger; oriental)

Pathogenesis
Fibre diet has inverse relationship with disease
Fibre = large 'residue' in bowel
Muscularis propria thickened (raised intraluminal pressure with empty colon)

Cx
Diverticulitis (leads to perforation/Abscesses)
Fistulae (*colovesical; ut/vaginal/abdo wall)
Intestinal obstruction fr inflammatory mass
Haemorrhage - diverticula *form where arteries enter muscPp